解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Japan is a super-ageing society that faces pressures on its aged care system from a growing population of older adults. Naturalistic observations were undertaken at eight aged care facilities in central and northern Japan to explore how aged care is configured. Four aspects of contemporary provision were identified th...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw144
更新日期:2016-11-01 00:00:00
abstract::Integrated care programs have been developed to enhance the quality care for older adults in primary care. These programs usually consist of a multidisciplinary approach, with personalised care based on comprehensive geriatric assessments. However, there is limited evidence for the effectiveness of these programs in f...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afw081
更新日期:2016-09-01 00:00:00
abstract::Explicit criteria, such as the STOPP/START criteria, are increasingly used both in clinical practice and in research to identify potentially inappropriate prescribing in older people. In an article on the STOPP/START criteria version 2, O'Mahony et al have pointed out the advantages of developing computerised criteria...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw114
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:delirium is under-recognised in comparison to other common and serious acute disorders. A 2006 survey of UK junior doctors (not undertaking specialist training) identified poor knowledge of the diagnostic criteria and treatment of delirium. We hypothesised that increased prominence accorded to delirium in th...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw066
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:to measure sex differences in the risk of receiving potentially inappropriate prescription drugs and to examine what are the factors that contribute to these differences. DESIGN:a retrospective cohort study. SETTING:community setting of British Columbia, Canada. PARTICIPANTS:residents of British Columbia ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw074
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:essential aspects of independence in community mobility among older people concern the control over where, when and how to participate (perceived autonomy), and actual mobility (life-space mobility; frequency, distance and need of assistance). We studied relationships between frailty and life-space mobility ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw072
更新日期:2016-07-01 00:00:00
abstract::We present two cases of acute hepatotoxicity associated with elevated paracetamol (acetaminophen) levels in older patients. Both patients were receiving a standard European dose of oral paracetamol (2 × 500 mg QDS) with no risk factors for slowed metabolism (weight <50 kg, interacting medications, hepatic enzyme induc...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw067
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:older people aged 80 and over are increasingly providing end-of-life care to spouses at home and often do so for long periods of time, while also trying to manage their own illnesses and disabilities. Little of the research on older spousal carers has focussed on the oldest carers; hence, the needs of this p...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw047
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement for patients with severe aortic stenosis considered inoperable or at high operative risk, but the long-term outcome remains unknown. HYPOTHESIS:we assessed the 4-year clinical and echocardiograp...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw038
更新日期:2016-05-01 00:00:00
abstract:AIMS/OBJECTIVES:to study associations between the likelihood of hospital death with patient demographics, cause of death and co-morbidities for people aged ≥85 at death who have been previously admitted (within 12 months of death) to hospital. METHODS:a cross-sectional study, using death registration data and hospital...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw019
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:thickened fluids are commonly advised to minimise the risk of aspiration in people with dysphagia, although many do not comply with this treatment. In health economics, utilities are values that reflect an individual's preferences for different health states. We examined the healthcare utilities, elicited us...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afv194
更新日期:2016-03-01 00:00:00
abstract::The General Medical Council (GMC) provides a core curriculum for all medical degrees in the UK. However, these guidelines do not provide in-depth, specific learning outcomes for the various medical specialties. Recognising our ageing population, the British Geriatrics Society in 2013 published their own supplementary ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw003
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:longitudinal analyses of physical activity (PA) and arterial stiffness in populations of older adults are scarce. We examined associations between long-term change of PA and arterial stiffness in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). METHODS:we assessed PA...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究
doi:10.1093/ageing/afv172
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Eating by oneself may be a risk factor for mental illness among older adults, but may be influenced by cohabitation status. We examined the association between eating alone and depression in the context of cohabitation status in older adults in Japan. DESIGN:A longitudinal, population-based study. SETTING:...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afv145
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:Routine cognitive screening for in-patients aged ≥75 years is recommended, but there is uncertainty around how this should be operationalised. We therefore determined the feasibility and reliability of the Abbreviated mental test score (AMTS/10) and its relationship to subjective memory complaint, Montreal...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afv134
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:previously, a randomised controlled exercise intervention study (RCT) showed that combined resistance and balance-jumping training (COMB) improved physical functioning and bone strength. The purpose of this follow-up study was to assess whether this exercise intervention had long-lasting effect...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afv064
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:high morale is defined as future-oriented optimism. Previous research suggests that a high morale independently predicts increased survival among old people, though very old people have not been specifically studied. OBJECTIVE:to investigate whether high morale is associated with increased survival among ve...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究
doi:10.1093/ageing/afv021
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:geriatrics encompasses diverse medical, social and ethical challenges requiring a multidimensional, interdisciplinary approach. Recent reports have highlighted failings in the care of older people. It is therefore vital that trainees in geriatrics are afforded opportunities to develop skills in managing this...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究
doi:10.1093/ageing/afv049
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:despite the vast literature in the area, few studies examined the large range of factors associated with physical activity (PA) in the older adult collectively, information that could help develop a supportive culture for healthy ageing. OBJECTIVE:to identify the socio-demographic, social connectedness, phy...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afv042
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The number of new world records has decreased substantially in most athletic events in recent years. There has been enormous growth in participation at Masters events, and older athletes have been competing at the highest levels with much younger athletes. However, the progression of athletic performance ove...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afv023
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Studies have raised concerns that medications with anticholinergic property have potential adverse effects on health outcomes. OBJECTIVES:The objective of this study is to examine the prospective relationships between total anticholinergic burden (ACB) from medications and mortality, and cardiovascular dise...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu185
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:To compare cognitive performance in participants with and without syncope and unexplained falls in a large population representative sample aged 50 years or older. METHODS:Participants of the Irish longitudinal study on ageing (TILDA) were studied. Participants with a history of syncope and/or unexplained fa...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu191
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS:We reviewed the 2008 STOPP/START criteria to add new evidence-based...
journal_title:Age and ageing
pub_type: 杂志文章,实务指引,评审
doi:10.1093/ageing/afu145
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Delirium is a complex neuropsychiatric syndrome that is common among elderly inpatients. It has been associated with increased mortality, longer hospital stays, cognitive and functional decline and increased institutionalisation rates. Multicomponent interventions, a series of non-pharmacological strategies ...
journal_title:Age and ageing
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ageing/afu173
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Delirium is a common neuropsychiatric disorder. The natural course is of an acute, fluctuating and often transient condition; however, accumulating evidence suggests that delirium can be associated with incomplete recovery. Despite a growing body of research, a lack of clarity exists regarding definition and...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afu152
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:animal studies suggest a neuroprotective role for leptin, but human studies have shown mixed results. We examined whether plasma leptin levels in individuals with mild cognitive impairment (MCI) were related to cognitive function at baseline and whether higher leptin levels were associated with reduced risk ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu160
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE:to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING:observational study of Clinic...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu113
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:polypharmacy is an important risk factor for falls, but recent studies suggest only when including medications associated with increasing the risk of falls. DESIGN:a prospective, population-based cohort study. SUBJECTS:6,666 adults aged ≥50 years from The Irish Longitudinal study on Ageing. METHODS:partic...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu141
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:home visits and telephone calls are two often used approaches in transitional care, but their differential economic effects are unknown. OBJECTIVE:to examine the differential economic benefits of home visits with telephone calls and telephone calls only in transitional discharge support. DESIGN:cost-effect...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afu166
更新日期:2015-01-01 00:00:00
abstract::There are few certainties in life-death is one of them. Yet death is often thought of today as the 'loss of the battle' against illness, where in traditional societies it was the natural, meaningful, end to life. Medical knowledge and technologies have extended the possibilities of medical care and increased our life ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu116
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:a fall occurs when an individual experiences a loss of balance from which they are unable to recover. Assessment of balance recovery ability in older adults may therefore help to identify individuals at risk of falls. The purpose of this 12-month prospective study was to assess whether the ability to recover...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu054
更新日期:2015-01-01 00:00:00
abstract:UNLABELLED:Older people are majority users of health and social care services in the UK and internationally. Many older people who access these services have frailty, which is a state of vulnerability to adverse outcomes. The existing health care response to frailty is mainly secondary care-based and reactive to the ac...
journal_title:Age and ageing
pub_type: 杂志文章,实务指引,评审
doi:10.1093/ageing/afu138
更新日期:2014-11-01 00:00:00
abstract:PURPOSE OF THE STUDY:to examine the costs and cost-effectiveness of 'second-generation' telecare, in addition to standard support and care that could include 'first-generation' forms of telecare, compared with standard support and care that could include 'first-generation' forms of telecare. DESIGN AND METHODS:a pragm...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/ageing/afu067
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:the aim of this study was to compare the effects of a functional tasks exercise programme to a cognitive training programme in older adults with mild cognitive impairment. DESIGN:a single-blind randomised control trial with the intervention group compared with an active control group. SETTING:out-patient cl...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afu055
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu111
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:residential aged care facility (RACF) resident numbers are increasing. Residents are frequently frail with substantial co-morbidity, functional and cognitive impairment with high susceptibility to acute illness. Despite living in facilities staffed by health professionals, a considerable proportion of reside...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afu117
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:vascular disease has been postulated to contribute to muscle dysfunction in old age. Previous studies examining the effects of cardiovascular drugs on muscle function have shown conflicting results. We therefore examined the association of angiotensin converting enzyme (ACE) inhibitor, thiazide and statin us...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu008
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:fractures are a major health concern among the elderly. People at risk for cardiovascular disease (CVD) are at an increased risk for fractures. The aim of this study was to assess the individual and combined effect of the CVD risk factors of smoking, alcohol consumption and physical activity on fracture risk...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究
doi:10.1093/ageing/afu009
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:national reports have highlighted deficiencies in care provided to older surgical patients and suggested a role for innovative, collaborative, inter-specialty models of care. The extent of geriatrician-led perioperative services in the UK (excluding orthogeriatric services) has not previously been describe...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu084
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:intracranial volume (ICV) is commonly used as a marker of premorbid brain size in neuroimaging studies as it is thought to remain fixed throughout adulthood. However, inner skull table thickening would encroach on ICV and could mask actual brain atrophy. OBJECTIVE:we investigated the effect that thickening ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu070
更新日期:2014-09-01 00:00:00